I love to play the blues but cant quite get that right sound out of my guitar and amp. Does anyone have any settings to share with me. Like the amp settings and so on.

There are a LOT of "Blues" tones. So, you have to ask yourself a few questions.
What kind of amp, and guitar are you using? Are there any famous players, songs, or recordings that could help to demonstrate the sounds you're thinking of?

I play a fat strat into a vox valvetronix or a roger linn adrenalinn 2. I would like to sound like Johnny Winters and SRV more electric texas blues style sound.

The strat should get you a good sound. Try the middle/bridge pickup selection. That will give you a nasally, out of phase sound that works great. I also prefer the neck pickup for a warmer sound.
I'm not experienced with the Valvetronix amp, but you could try the Fender type settings. If there is a Deluxe Reverb setting, or a Tweed Bassman setting, you can get some pretty good approximations. Also, you could try a TS type of pedal.
Also, you should listen to a lot of different players. Try Freddie King, Buddy Guy, Lonnie Mack, Albert Collins. The more variety you hear, the easier it will be to see the possibilities.

I use a Les Paul Custom (not similar to a strat) into a Tonelab SE (very similar to Valvetronix). When I want the SRV type tone, I use the Tube OD (TS-808 model) into Tweed 4X10 amp and cab models.

yeah but what are your tone settings like bass mid ect.

Pedal is a Tube Screamer
Pedal: Tube OD
Drive: 7.0
Level: 5.1
Tone: 7.8

For rhythm, I back my neck pickup off a bit to clean it up. If you're using a strat, that might not be necessary.
Chan A: Tweed 4X10 (Rhythm)
Gain: 5.1
VRGain: 10.0
Treble: 8.7
Mid: 1.5
Bass: 1.4
Presence: 9.3
ChVol: 5.0
Cab: Vox AD412
NR Sens: 6.8

For lead, open it up full.
Chan B: Tweed 4X10 (Lead)
Gain: 6.9
VRGain: 10.0
Treble: 8.5
Mid: 3.1
Bass: 1.2
Presence: 9.1
ChVol: 5.6
Cab: Vox AD412
NR Sens: 8.2

This modulator (connected to the control on/off switch) will (sort of) do the Cold Shot effect. I would rather use the Uvibe, but it's not available when using the OD.

Mod: Classic Choir
Speed: 5.80 hz
Depth: 6.8
Manual: 1.0
Mode: 1

Use delay for an echoplex effect, reverb as desired.